Anti-CARD8 Polyclonal Antibody
产品名称： Anti-CARD8 Polyclonal Antibody
英文名称： Anti-CARD8 Polyclonal Antibody
产品编号： K001666P
产品价格： null
产品产地： 北京
品牌商标： solarbio
更新时间： 2025-01-17T10:18:30
使用范围： WB
北京索莱宝科技有限公司
- 联系人 : 索莱宝-龚思雨
- 地址 : 北京市通州区中关村科技园区通州园金桥科技产业基地景盛南四街15号85A三层
- 邮编 : 101102
- 所在区域 : 北京
- 电话 : 178****1073 点击查看
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- 邮箱 : 3193328036@qq.com
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Anti-CARD8 Polyclonal Antibody
品牌：solarbio | 货号：K001666P
| 英文名称 | Anti-CARD8 Polyclonal Antibody |
|---|---|
| 别名 | CARDINAL;DACAR;DAKAR;NDPP;NDPP1;TUCAN |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 49kDa |
| Gene ID | 22900 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human CARD8 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human CARD8 |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | Q9Y2G2 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene. |