PCK2 polyclonal antibody
产品名称： PCK2 polyclonal antibody
英文名称： PCK2 polyclonal antibody
产品编号： PAB6875
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of PCK2.
- Immunogen:
- A synthetic peptide corresponding to human PCK2.
- Sequence:
- KPWKPGDKEPCAH
- Host:
- Goat
- Theoretical MW (kDa):
- 70.7
- Reactivity:
- Human
- Specificity:
- This antibody is expected to recognize isoform 1 (NP_004554) only, no cross-reactivity with PCK1.
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:8000)
Western Blot (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Expression of phosphoenolpyruvate carboxykinase gene in human adipose tissue: induction by rosiglitazone and genetic analyses of the adipocyte-specific region of the promoter in type 2 diabetes.
Duplus E, Benelli C, Reis AF, Fouque F, Velho G, Forest C.Biochimie. 2003 Dec;85(12):1257-64.
- Entrez GeneID:
- 5106
- Protein Accession#:
- NP_004554.2
- Gene Name:
- PCK2
- Gene Alias:
- PEPCK,PEPCK-M,PEPCK2
- Gene Description:
- phosphoenolpyruvate carboxykinase 2 (mitochondrial)
- Omim ID:
- 261650
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the phosphoenolpyruvate carboxykinase (GTP) family. The protein is a mitochondrial enzyme that catalyzes the conversion of oxaloacetate to phosphoenolpyruvate in the presence of GTP. A cytosolic form encoded by a different gene has also been characterized and is the key enzyme of gluconeogenesis in the liver. The encoded protein may serve a similar function, although it is constitutively expressed and not modulated by hormones such as glucagon and insulin that regulate the cytosolic form. Alternatively spliced transcript variants have been described. [provided by RefSeq
- Other Designations:
- OTTHUMP00000164700,PEP carboxykinase,mitochondrial phosphoenolpyruvate carboxykinase 2,phosphoenolpyruvate carboxylase,phosphopyruvate carboxylase
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