PML monoclonal antibody, clone B4C8
产品名称： PML monoclonal antibody, clone B4C8
英文名称： PML monoclonal antibody, clone B4C8
产品编号： MAB8132
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against recombinant PML.
- Immunogen:
- Recombinant protein corresponding to human PML.
- Host:
- Mouse
- Reactivity:
- Human
- Form:
- Lyophilized
- Isotype:
- IgG1
- Storage Buffer:
- Lyophilized from 10 mM PBS
- Storage Instruction:
- Store at -20°C.
Aliquot after reconstitution to avoid repeated freezing and thawing.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Application Image
- Western Blot
- Enzyme Immunoassay
- Entrez GeneID:
- 5371
- Gene Name:
- PML
- Gene Alias:
- MYL,PP8675,RNF71,TRIM19
- Gene Description:
- promyelocytic leukemia
- Omim ID:
- 102578
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor. Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals. The gene is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL). Extensive alternative splicing of this gene results in several variations of the protein's central and C-terminal regions; all variants encode the same N-terminus. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
- Other Designations:
- promyelocytic leukemia protein,promyelocytic leukemia, inducer of,tripartite motif protein TRIM19