ITGAX monoclonal antibody, clone BU15 (PerCP)
产品名称： ITGAX monoclonal antibody, clone BU15 (PerCP)
英文名称： ITGAX monoclonal antibody, clone BU15 (PerCP)
产品编号： MAB4353
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against native ITGAX.
- Immunogen:
- Native purified ITGAX from human dendritic cells of synovial fluid.
- Host:
- Mouse
- Theoretical MW (kDa):
- 150
- Reactivity:
- Dog, Human, Monkey
- Specificity:
- This antibody reacts with ITGAX, a 150 KDa integrin expressed mainly on dendritic cells and tissue macrophages.
- Form:
- Liquid
- Conjugation:
- PerCP
- Isotype:
- IgG1
- Storage Buffer:
- In PBS (0.2% BSA, 15 mM sodium azide)
- Storage Instruction:
- Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Flow Cytometry (10 ul in human blood cells 100 ul in whole blood or 106 cells in a suspension)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Novel tools for functional analysis of CD11c: activation-specific, activation-independent, and activating antibodies.
Sadhu C, Hendrickson L, Dick KO, Potter TG, Staunton DE.J Immunoassay Immunochem. 2008;29(1):42-57.
- 2.
- Regulation of adhesion of AML14.3D10 cells by surface clustering of beta2-integrin caused by ERK-independent activation of cPLA2.
Myou S, Zhu X, Boetticher E, Qin Y, Myo S, Meliton A, Lambertino A, Munoz NM, Hamann KJ, Leff AR.Immunology. 2002 Sep;107(1):77-85.
- 3.
- Ligation of CD11b and CD11c beta(2) integrins by antibodies or soluble CD23 induces macrophage inflammatory protein 1alpha (MIP-1alpha) and MIP-1beta production in primary human monocytes through a pathway dependent on nuclear factor-kappaB.
Rezzonico R, Imbert V, Chicheportiche R, Dayer JM.Blood. 2001 May 15;97(10):2932-40.
- Entrez GeneID:
- 3687
- Gene Name:
- ITGAX
- Gene Alias:
- CD11C,SLEB6
- Gene Description:
- integrin, alpha X (complement component 3 receptor 4 subunit)
- Omim ID:
- 151510
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. [provided by RefSeq
- Other Designations:
- OTTHUMP00000163299,integrin alpha X,integrin, alpha X (antigen CD11C (p150), alpha polypeptide),leu M5, alpha subunit,leukocyte surface antigen p150,95, alpha subunit,myeloid membrane antigen, alpha subunit,p150 95 integrin alpha chain
- Gene Pathway