FITC标记的纤维母细胞生长因子5抗体
产品名称： FITC标记的纤维母细胞生长因子5抗体
英文名称： Anti-FGF5/FITC
产品编号： HZ-1257R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-FGF5/FITC Conjugated antibody
FITC标记的纤维母细胞生长因子5抗体
| 英文名称 | Anti-FGF5/FITC |
| 中文名称 | FITC标记的纤维母细胞生长因子5抗体 |
| 别 名 | FGF 5; FGF-5; FGF5; FGF5_HUMAN; fibroblast growth factor 5; HBGF 5; HBGF-5; heparin binding growth factor 5; Heparin-binding growth factor 5; Smag 82; Smag-82. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 免疫学 转录调节因子 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Cow, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 78kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human FGF5 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified as an oncogene, which confers transforming potential when transfected into mammalian cells. Targeted disruption of the homolog of this gene in mouse resulted in the phenotype of abnormally long hair, which suggested a function as an inhibitor of hair elongation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]. Function: Functions as an inhibitor of hair elongation by promoting progression from anagen, the growth phase of the hair follicle, into catagen the apoptosis-induced regression phase. Subunit: Interacts with FGFR1 and FGFR2. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors. Subcellular Location: Secreted. Tissue Specificity: Expressed in neonatal brain. Similarity: Belongs to the heparin-binding growth factors family. Database links: Entrez Gene: 2250 Human Omim: 165190 Human SwissProt: P12034 Human Unigene: 37055 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. FGF5是FGF家族的成员，有诱导癌变转化作用。FGF家族参与一系列的生理功能：胚胎发育、细胞生长、器官形成、组织修复、肿瘤生长和侵袭 |
由该基因编码的蛋白质是成纤维细胞生长因子（FGF）家族的成员。FGF家族成员具有广泛的有丝分裂和细胞存活活性，参与多种生物学过程，包括胚胎发育、细胞生长、形态发生、组织修复、肿瘤生长和侵袭。该基因被鉴定为一种致癌基因，该基因在转染哺乳动物细胞时赋予转化潜能。该基因的同源物在小鼠中的靶向性破坏导致异常长毛的表型，这表明其作为毛发伸长的抑制剂的功能。另一种编码不同的异构体的剪接转录变体已被鉴定。[由RefSeq提供]。