1) Cat. No.: TRC-N407767; 2) Chemical Name: β-Nicotinamide Mononucleotide-13C5; 3) CAS No.: ; 4) Mol. Formula: C613C5H15N2O8P; 5) Mol. Weight: 339.18; 6) Packing Size: 25mg / 50mg; 7) Appearence: ; 8) Application Notes: The labelled analogue of a product of the extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. It also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation.; 9) Synonym: 3-(Aminocarbonyl)-1-(5-O-phosphono-β-D-ribofuranosyl)pyridinium-13C5 Inner Salt;
3-Carbamoyl-1-β-D-ribofuranosylpyridinium Hydroxide 5'-Phosphate-13C5 Inner Salt; NMN-13C5; Nicotinamide Mononucleotide-13C5; Nicotinamide Ribonucleoside 5'-Phosphate-13C5; Nicotinamide Ribonucleotide-13C5; Nicotinamide Ribotide-13C5; β-D-NMN-13C5; β-NMN-13C5;; 10) Solubility: ; 11) Storage condition: ; 12) References: Yoshino, J. et al.: Cell Metab., 14, 528 (2011); Caton, P.W. et al.: Diabetologia, 54, 3083 (2011); Formentini, L. et al.: BIochem. Pharmacol., 77, 1612 (2009);