Vasoactive Intestinal Peptide Antibody
产品名称: Vasoactive Intestinal Peptide Antibody
英文名称: Vasoactive Intestinal Peptide Antibody
产品编号: 250236
产品价格: null
产品产地: 美国
品牌商标: Abbiotec
更新时间: null
使用范围: The dilution guideline of 1:1,000 applies to VIP coated directly at 2 g/mL. For glutaraldehyde-linked VIP-ovalbumin (mol
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Vasoactive intestinal peptide (VIP) is a 28-amino-acid peptide belonging to the secretin-glucagon family of peptide hormones. Its sequence is identical in man, ox, pig and rat. VIP is widely distributed in the central and peripheral nervous systems, acting as a neurotransmitter or neuromodulator. Peripherally it is involved in vaso- and bronchodilatation, smooth muscle relaxation and stimulation of secretion. Ectopic endocrine tumors secreting VIP (VIPomas) give rise to raised plasma levels of VIP and are associated with watery diarrhea, hypokalemia and achlorhydria syndrome. VIP shows high sequence homology with peptide histidine-methionine (PHM) in man or peptide histidine-serine (PHI) in pigs or rats, present in the same precursor, and with the neuropeptide pituitary adenylate cyclase activating polypeptide (PACAP). This antibody binds to human, bovine, porcine or rat VIP, but does not bind to PHM or PACAP.