FITC标记的SAMSN1蛋白抗体
产品名称： FITC标记的SAMSN1蛋白抗体
英文名称： Anti-SAMSN1/FITC
产品编号： HZ-9379R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-SAMSN1/FITC Conjugated antibody
FITC标记的SAMSN1蛋白抗体
| 英文名称 | Anti-SAMSN1/FITC |
| 中文名称 | FITC标记的SAMSN1蛋白抗体 |
| 别 名 | HACS1; Hematopoietic adapter containing SH3 and sterile α motif (SAM) domains 1; Hematopoietic adapter containing SH3 and sterile alpha motif (SAM) domains 1; hematopoietic adaptor containing SH3 and SAM domains 1; NASH1; Nuclear localization signals SAM and SH3 domain containing 1; SAM and SH3 domain containing 2; SAM domain; SAM domain containing protein SAMSN 1; SAM domain SH3 domain and nuclear localisation signals 1; SAM domain SH3 domain and nuclear localization signals 1; SAM domain, SH3 domain and nuclear localization signals protein 1; SAM domain-containing protein SAMSN-1; SAMN1_HUMAN; SAMSN 1; Samsn1; SASH2; SH3 domain and nuclear localisation signals 1; SH3 domain and nuclear localization signals protein 1; SH3 SAM adaptor protein; SH3-SAM adaptor protein; SH3D6B; SLy2; Src homology domain 3 (SH3) containing adapter protein SH3 lymphocyte protein 2. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 干细胞 细胞分化 b-淋巴细胞 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Dog, Cow, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 42kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SAMSN1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: SAMSN1 is a member of a novel gene family of putative adaptors and scaffold proteins containing SH3 and SAM (sterile alpha motif) domains (Claudio et al., 2001 [PubMed 11536050]).[supplied by OMIM, Mar 2008] Function: Negative regulator of B-cell activation. Down-regulates cell proliferation (in vitro). Promotes RAC1-dependent membrane ruffle formation and reorganization of the actin cytoskeleton. Regulates cell spreading and cell polarization. Stimulates HDAC1 activity. Regulates LYN activity by modulating its tyrosine phosphorylation. Subcellular Location: Nucleus. Cytoplasm. Cell projection > ruffle. Shuttles between cytoplasm and nucleus. Colocalizes with the actin cytoskeleton and actin-rich membrane ruffles. Tissue Specificity: Detected in peripheral blood B-cells (at protein level). Detected in spleen, liver and peripheral blood. Similarity: Contains 1 SAM (sterile alpha motif) domain. Contains 1 SH3 domain. Database links: Entrez Gene: 418470 Chicken Entrez Gene: 64092 Human Entrez Gene: 67742 Mouse Entrez Gene: 170637 Rat NCBI: 48762709 Human Omim: 607978 Human SwissProt: Q9NSI8 Human SwissProt: P57725 Mouse Unigene: 473341 Human Unigene: 719474 Human Unigene: 131406 Mouse Unigene: 81187 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
SAMSN1是含有SH3和SAM(无菌阿尔法基序)结构域的推定适配子和支架蛋白的新基因家族的成员(Claudio等人，2001[PubMed 11536050])。