SEPP1 monoclonal antibody, clone 37A1
产品名称： SEPP1 monoclonal antibody, clone 37A1
英文名称： SEPP1 monoclonal antibody, clone 37A1
产品编号： MAB0761
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against native SEPP1.
- Immunogen:
- Native purified human SEPP1.
- Host:
- Mouse
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Ammonium sulfate precipitation
- Concentration:
- 1 mg/mL
- Isotype:
- IgG1, kappa
- Storage Buffer:
- In HEPES, 150 mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:2000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- S-Adenosylmethionine Dependent Protein Methylation is Required for Expression of Selenoprotein P and Gluconeogenic Enzymes in Human Hepatocytes.
Jackson MI, Cao J, Zeng H, Uthus EO, Combs GF Jr.J Biol Chem. 2012 Aug 29.
- 2.
- Chemical Form of Selenium Affects Its Uptake, Transport, and Glutathione Peroxidase Activity in the Human Intestinal Caco-2 Cell Model.
Zeng H, Jackson MI, Cheng WH, Combs GF Jr.Biol Trace Elem Res. 2010 Dec 23. [Epub ahead of print]
- 3.
- Involvement of selenoprotein P in protection of human astrocytes from oxidative damage.
Steinbrenner H, Alili L, Bilgic E, Sies H, Brenneisen P.Free Radic Biol Med. 2006 May 1;40(9):1513-23. Epub 2006 Jan 13.
- Entrez GeneID:
- 6414
- Gene Name:
- SEPP1
- Gene Alias:
- SELP,SeP
- Gene Description:
- selenoprotein P, plasma, 1
- Omim ID:
- 601484
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a selenoprotein containing multiple selenocysteine (Sec) residues, which are encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This selenoprotein is an extracellular glycoprotein, and is unusual in that it contains 10 Sec residues per polypeptide. It is a heparin-binding protein that appears to be associated with endothelial cells, and has been implicated to function as an antioxidant in the extracellular space. Several transcript variants, encoding either the same or different isoform, have been found for this gene. [provided by RefSeq
- Other Designations:
- selenoprotein P
- Related Disease
- Adenocarcinoma
- Adenoma
- Alzheimer Disease
- Alzheimer disease
- Cognition
- Colon cancer
- Colorectal Neoplasms
- Disease Susceptibility
- Genetic Predisposition to Disease
- Lung Neoplasms
- Neoplasms
- Osteoarthritis
- Ovarian cancer
- Prostate cancer
- Prostatic Neoplasms
- Pulmonary Disease, Chronic Obstructive
- Urinary Bladder Neoplasms
- Werner syndrome